eeeCharlesDexterWard'swifeenliststhehelpofaprivatedetectivetofindoutwhatherhusbandisuptoinaremotecabinownedbyhisfamilyforcenturies.The husbandisachemicalengineer|andthesmellsfromhisexperiments(andthedeliveryofwhatappeartobehumanremainsatallhours)arebeginningtoarousethe attentionofneighborsandlocallawenforcementofficials.Whenthedetectiveandwifefindadiaryofthehusband'sancestorfrom1771|andreportsofgruesome murdersintheareabegintosurface|theybegintosuspectthatsomeveryunnaturalexperimentsarebeingconductedintheoldhouse.BasedonanH.P.Lovecraft